Aromatic Compounds and Substitution Reactions

Topic

Structure

Aromaticity rules

Frost circle diagrams

Substituents, Resonance, and electronic effects

Introduction to electrophilic aromatic substitution (EAS)

Bromination

Chlorination

Nitration

Sulfonylation

Friedel-Crafts alkylation

Friedel-Crafts acylation

Diazonium salt reactions

Nucleophilic aromatic substitution

The benzyne mechanism

Heterocycles and EAS